Objective To develop evidence-based health science popularization works for the prevention of deep vein thrombosis（DVT） in patients after joint replacement. Methods In this study，guided by the Guideline International Network patient guideline formulation manual and Patient Education Materials Assessment Tool，we conducted semi-structured interviews to clarify the health science themes. These themes were matched with relevant evidence，and the relevant evidence recommendation items for each theme were refined. It is translated into easily understandable language and other forms. 12 representatives（doctor，nurse，patient，science popularization expert and evidence-based methodology expert） conducted an external review of the quality of these science popularization works. Results Prevention of post-operative DVT，patients’ main concerns and the most urgent need for action were extracted from a total of 6 scientific topics. After the matching with 22 pieces of evidence，a health education content system for the prevention of DVT after total joint arthroplasty was created. According to the system framework and evidence，as well as the preferences and needs of patients，a popular science manual and popular science video were created，with the final external review rate of 94%~100% and the coefficient of variation of 0~0.101. The revised health science works for the prevention of DVT after joint replacement included popular science manuals-trifolds and popular science videos. The copyright of both popular science manuals（copyright number：Guozuo Dengzi-2022-L-10159159） and popular science videos（copyright number：Guozuo Dengzi-2022-I-10162339） have been registered. Conclusion The method of developing science popularization works on the prevention of DVT in patients after joint replacement is scientific. It can provide a methodological reference for the development of other science popularization works.

Objective To evaluate and summarize the best evidence for ultrasound-guided nasointestinal tube placement in adult critically ill patients，and to provide references for clinical practice. Methods The relevant evidence of ultrasound-guided nasointestinal feeding tube placement in adult critically ill patients was systematically searched from domestic and foreign databases and websites，including guidelines，expert consensuses，clinical decision-making，evidence summaries and systematic reviews，and the search time limit is from the establishment of the databases to June，2022. There were 2 researchers who independently assessed the quality of the literature and identified the level of evidence. Results A total of 22 articles were included，including 5 guidelines，6 expert consensuses，1 group standard，2 clinical decision-making，3 evidence summaries and 5 systematic reviews. 26 pieces of evidence were summarized from 5 themes：clinical situation，assessment，preparation，key points of catheterization，and nursing essentials. Conclusion The best evidence of ultrasound-guided nasointestinal tube placement in adult critically ill patients was summarized to provide evidence-based references for the implementation of bedside ultrasound-guided nasointestinal feeding tube placement and ensure patient safety.

Objective A scoping review of studies on critical diaphragmatic dysfunction at home and abroad was conducted to grasp the current state of research in the topic. Methods In accordance with the scope review’s research methodologies，databases including PubMed，Embase，Web of Science，CNKI，and Wan fang were searched by the computer for relevant studies. The deadline for retrieval is from the establishment of databases to September 4，2022. There was an analysis of the included literature. Results 39 articles were finally included. Two of them were historical cohort studies，while the other 37 were prospective ones. The conceptual spectrum of diaphragm dysfunction includes eventration，frailty，and paralysis of the diaphragm. The evaluation procedures included ultrasound of the diaphragm and bilateral phrenic nerve stimulation. Diaphragm thickness fraction，diaphragm movement，abnormal diaphragm movement，and endotracheal pressure induced by phrenic nerve stimulation are the primary evaluation indicators. Conclusion Domestic nursing researchers should focus on the problems and complications associated with diaphragmatic dysfunction in severely ill patients，select a standardized and unified evaluation method，and use a variety of indicators to comprehensively evaluate the diaphragm function of patients in order to better treat patients and aid in their early recovery.

Objective To explore the expert consensus on risk assessment and preventive nursing of venous thromboembolism（VTE） in general surgical patients. Methods This consensus was drafted through a systemic literature review on VTE prevention and the interviews of nursing experts. The draft was thereafter reviewed by a total of experts in related fields,and it was finalized after 2 rounds of expert consultation. Results 4 domains with 26 components were established through a modified Delphi method. The effective recovery of the ques-tionnaire was 100%;the expert judgment coefficient was 0.960;the familiarity was 0.912;the authority coefficient was 0.936. The Kendall coefficients of the first and second level topics in the 2 rounds were 0.149 and 0.261,and 0.122 and 0.203,respectively,with statistically significant differences（P<0.05）. The consensus includes risk factors for VTE in general surgical patients,risk assessment,risk response,education and quality control,and it is applicable to perioperative patients of general surgery. Conclusion The consensus was based on the recommendations of 25 clinical nursing experts. The results are scientific,rigorous and authoritative,and can provide guidance for clinical nursing staff in the prevention and control of VTE in general surgical patients.

Objective To carry out evidence-based nursing for the prevention of deep vein thrombosis（DVT） in patients after joint replacement，to formulate review indicators，to analyze the obstacles and promoting factors in the practice of evidence-based nursing，and to formulate action strategies. Methods Based on the Knowledge to Action framework as the theoretical guidance，a total of 24 pieces of evidence for DVT prevention nursing in patients after joint replacement in suitable clinical situations were included；6 examination criteria and 33 examination indexes were formulated；the preventive behavior of nurses was observed on-site with patients as a unit. Furthermore，based on the results of the baseline review，brainstorming was used to analyze the barriers and facilitators in evidence-based practice，and action strategies were formulated. Results Totally 24 pieces of best evidence were included. According to the best evidence，33 examination indexes and 6 examination criteria were established. The clinical compliance rate of the 6 examination criteria ranges from 0% to 100%. Among them，there is room for improvement in health education（0），mechanical prevention（62%），pharmacological prevention（81%） and quality control（21%）. Obstacle factors include the lack of tools and nursing processes，lack of knowledge，insufficient attention，busy work，as well as low understanding and low participation. Facilitating factors include strong organizational leadership，medical team cooperation，sufficient equipment，etc. Accordingly，corresponding action strategies have been formulated. Conclusion Based on evidence and clinical experience，we formulated the scientific，appropriate and maneuverable indicators. At present，there is a certain gap between the evidence for the prevention of deep vein thrombosis in patients after joint replacement，and we should fully utilize these facilitating factors，overcome obstacles，implement improving measures，and promote the effective application of evidence.

This paper reviews the existing assessment tools，outlines the development process，main contents，and application status of universal and disease-specific health-related quality of life assessment tools for patients with DVT，analyzes the characteristics and limitations of existing tools，and aims to provide references for clinical selection of appropriate assessment tools and for the development of health-related quality of life assessment tools for patients with DVT in accordance with the cultural background of China.

Objective To systematically evaluate the safety and effectiveness of enteral nutrition in patients with prone ventilation,and to provide references for clinical decision-making. Methods CNKI,WanFang,VIP,SinoMed,PubMed,Embase,Cochrane Library,Web of Science,Clinic trials were searched for randomized controlled trials,quasi-experimental studies and cohort studies about the safety and efficacy of enteral nutrition in patients with prone ventilation published from inception to January 2021. There were 2 reviewers who screened the literature according to the inclusion and exclusion criteria,extracted data,and assessed the quality of included studies indepen-dently. Meta-analysis was conducted by RevMan 5.4. Results Finally,9 articles are included,with a total of 461 patients. The results of meta-analysis showed that compared with patients with supine position,there was no statistical significance for patients with enteral nutrition during prone position in the incidence of high gastric residual volume[OR=0.89,95%CI（0.57,1.38）,P=0.60],the incidence of vomiting or reflux[RR=1.15,95%CI（0.89,1.48）,P=0.29],ventilator associated pneumonia[RR=1.18,95%CI（0.77,1.81）,P=0.44],enteral nutrition interruption rate[RR=1.42,95%CI（0.90,2.24）,P=0.13],length of stay in ICU[MD=-0.63,95%CI（-5.94,4.68）,P=0.82]. Conclusion Enteral nutrition in prone patients had no significant effect on the incidence of high gastric residual volume,vomiting or regurgitation,ventilator-associated pneumonia,enteral nutrition interruption,or length of ICU stay. However,the quality of the included literature is limited,and more high-quality clinical studies are needed for further validation in the future.

Objective To comprehensively retrieve and analyze evidence related to deep vein thrombosis（DVT）prevention after joint replacement and to summarize the best evidence. Methods We systematically searched for evidence on DVT prevention after joint replacement in BMJ Best Practice,UpToDate,JBI,YiMaiTong,GIN,NGC,NZGG,NICE,SIGN,NHMRC,CPG Infobase,CINAHL,EMBASE,PubMed,WOS,Wanfang and CNKI databases to collect relevant clinical decisions,evidence summaries,clinical guidelines and expert consensuses. The timeframe of data search ran from January 2015 to November 2020. 2 researchers independently evaluated the quality of the articles,and classified the evidence according to the Joanna Briggs Institute evidence-based pre-grading system（2014 edition）. Results A total of 13 articles were included,including 3 clinical decisions,2 evidence summaries,4 guidelines and 4 expert consensuses. Combined with professional judgment,16 pieces of best evidence in 6 aspects were summarized,including risk assessment,health education,preventive measures of nursing care,mechanical prophylaxis,pharmacological prophylaxis,and promotion of clinical implementation of preventive measures. Conclusion The best evidence summarized on the prevention of DVT in patients after joint replacement can provide evidence for clinical nursing work.

Objective To search,evaluate and summarize the best evidence of the related operation techniques for electronic measurement of central venous pressure（CVP）. Methods According to the “6S” pyramid model,the computer literature retrieval was carried out by using evidence-based nursing method,including guidelines,recommended practices,evidence summaries,expert consensuses,randomized controlled studies,etc. The search time is from 1 January 2005 to 31 December 2020. 2 researchers independently evaluated the literature quality using the appraisal of guidelines for research and evaluation Ⅱ and the corresponding evaluation standard（2016） of JBI Evidence-based Health Care Center in Australia. Combined with the judgment of professionals,the qualified literature was extracted and graded according to JBI Evidence Pre-grading System（2014 edition）. Results A total of 28 pieces of literature were included,including 2 guidelines,4 expert consensuses,4 systematic reviews,13 randomized controlled studies,1 diagnostic test and 4 descriptive cross-sectional studies. Evidence was summarized from 7 aspects,including access selection,elimination of other interference factors,patient position,sensor zero calibration and position,analysis of waveform and accurate reading,equipment management and personnel training,and 30 pieces of best evidence were formed. Conclusion This paper summarizes the best evidence of relevant operating techniques of CVP electronic measurement,which provides an evidence basis for improving the accuracy and operation standardization of clinical CVP measurement.

Objective To evaluate the effectiveness of ICU diary on mental health status of ICU patients and their family members. Methods Randomized controlled trials on the effectiveness of ICU diary on post-traumatic stress disorder, anxiety and depression of ICU patients and their family members were retrieved from electronic databases of PubMed, Embase, Web of Science, Cochrane Library, CBM, CNKI, Wanfang data and VIP. RevMan 5.3 software was used to perform meta-analysis. Results 8 studies were included for systematic review and meta-analysis. The results showed that ICU diary group reported significantly lower incidences of post-traumatic stress disorder[RR=0.65（95%CI:0.51~0.82）, P<0.001] and depression[RR=0.65（95%CI:0.45~0.92）, P=0.02]. There was no significant difference between anxiety[RR=0.69（95%CI:0.31~1.52）, P=0.36] among ICU patients and post-traumatic stress disorder[RR=0.76（95%CI:0.33~1.74）, P=0.51] among family members of ICU patients. In addition, there is no significant difference in the incidences of depression and anxiety among family members according to descriptive analysis. Conclusion ICU diary could reduce the incidence of post-traumatic stress disorder and depression among ICU patients but not the incidence of post-traumatic stress disorder, depression, anxiety among family members. Due to the limitations of methodological quality and sample size of the included studies, the original studies with high quality and large sample size are still needed to be carried out in the future to further evaluate the effectiveness of ICU diary.

Objective To explore the nursing human resources management strategies of the medical aid team to Hubei during the coronavirus disease 2019（COVID-19） epidemic and to improve the efficiency of nursing management. Methods Drawing on the command and decision-making system of health emergencies,and taking "emergency support-basis-action" as the conceptual model of nursing manpower management,we constructed a scientific,effective and practical ICU nursing manpower management model. Results There were 135 members in nursing aid team with 7 nursing groups being established to implement flexible management. Progressive trainings were carried out and clinical teaching was conducted for 30 times. A total of 109 critically ill patients with COVID-19 were admitted,including 75 patients with mechanical ventilation. Conclusion In response to the outbreak of COVID-19,the national medical aid team quickly established ICU nursing team,and formed a management model of nursing manpower based on "emergency support-basis-action" model to protect the critically ill patients with COVID-19 and to ensure the patients treatment and care being carried out smoothly.

Objective To establish an expert consensus on nursing prevention and control of venous thromboembolism（VTE） in adult patients with coronavirus disease 2019（COVID-19）. Methods This consensus was drafted through a systemic literature review on COVID-19 diagnosis and management plan,VTE prevention and control,and interviewing nursing experts from front-line epidemic control. The draft was thereafter reviewed by a total of 18 experts in related fields. This consensus was finalized after 2 rounds of discussions and modifications. Results The expert consensus covers the following 5 topics,namely VTE risk factors,VTE risk assessment,VTE nursing prevention and control,VTE prewarning and monitoring,and health care education of VTE prevention and control after discharge. Conclusion The consensus was drafted and finalized on a scientific and practical basis,which can provide guidance for clinical nurses in prevention and control of VTE in adult patients with COVID-19.

Objective To determine the prevalence and risk factors of subsyndromal delirium （SSD） in adult intensive care unit patients by systematically reviewing evidence. Methods PubMed,Embase,PsycINFO,Cochrane Library,CBM,CNKI,VIP and Wanfang were searched from inception to 2019 for potentially relevant articles. Stata 14.0 software was used to analyze the prevalence of subsyndromal delirium with a single group meta-analysis. Fixed-effect or random-effect models were used to merge data. Begg rank correlation and funnel plot were used to determine publication bias. Descriptive analysis was used to analyze the influencing factors. Results 13 studies（5396 ICU patients） were included. The combined prevalence of subsyndromal delirium was 36.9%[95%CI（0.22~0.52）]. Subgroup analysis showed that the prevalence of subsyndromal syndrome was higher in women,elderly ICU and patients Asia. Possible risk factors included age,severity of diseases,cognitive impairment,and drug sedation. Conclusion There is a certain prevalence of subsyndromal delirium in ICU patients（36.9%）. Age,underlying diseases,cognitive impairment,and drug sedation are possible risk factors. However,the overall sample size of the study is not large and the quality of the study is quite poor. It is suggested that large-sample multi-centered studies should be carried out in future to further explore the prevalence and risk factors of subsyndromal delirium in ICU patients.